The Tetracyclines are a group of broad-spectrum antibiotics efficient against Gram-positive and Gram-negative bacteria, anaerobic and intracellular microorganisms. Their mechanism of action is the inhibition of proteic synthesis...
...These antibiotics are widely used in veterinary medicine to prevent and control some breeding animals pathologies. Treatments, if the appropriate withdrawal time is not respected, can lead to residues in foods of animal origin. With the Regulation 2377/90 the European Council has established the MRL (Maximum Residue Limits) for this group of antimicrobial drugs: 100 ppb for milk and muscle, 200 ppb for eggs, 300 ppb for liver and 600 ppb for kidney. Since the use of antibiotics in apiculture is forbidden, there is not a MRL for honey. _In Germany the concentration above which the Public Health claims that the honey is not-compliant is set at 20ppb.
In order to meet the market demand of a more sensitive screening method, Tecna has developed a new receptor kit:
SuperScreen TETRA HS (cod. AB710-AB711), with extremely low detection limits.
Validation tests confirm the good performances of the kit, which has excellent CCbeta in food matrices (honey 10 ppb, milk 15 ppb, pig muscle 10 ppb). The new kit includes the procedures and reagents needed to detect tetracyclines residue in various food matrices such as: honey, milk, muscle and meat drip.
Thanks to the wide cross-reactivities range, the kit enables the contemporary analyses of many antibiotics (tetracycline, oxytetracycline, chlortetracycline and doxicycline), simplifying and making faster the analyses. The excellent detection of doxicycline (active principle registered in many countries), residue that can easily escape in ELISA, is one of relevant features of the product. The measuring range includes all the established regulatory limits (for honey, milk and tissues); assuring the maximum performance and reliability. The sample preparation is simple and does not require any purification by columns.
For further information about
SuperScreen Tetra HS (cod. AB710-AB711), download the data sheet in the section "Products"